Noninvasive Imaging in Myocarditis
نویسندگان
چکیده
منابع مشابه
Noninvasive imaging in myocarditis.
Increased recognition of the role of inflammation in acute and chronic dilated cardiomyopathy has revived an interest in noninvasive imaging for detection of myocarditis. Diagnostic strategies that are based on molecular imaging promise to further advance our understanding and improve diagnostic precision. This article reviews the strengths and limitations of common clinical tests used for the ...
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BACKGROUND Cardiac tests for diagnosing myocarditis lack sensitivity or specificity. We hypothesized that contrast-enhanced ultrasound molecular imaging could detect myocardial inflammation and the recruitment of specific cellular subsets of the inflammatory response in murine myocarditis. METHODS AND RESULTS Microbubbles (MB) bearing antibodies targeting lymphocyte CD4 (MBCD4), endothelial P...
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The ability of 67Ga citrate and 99mTc pyrophosphate cardiac imaging to detect myocarditis was assessed in an experimental rabbit model. Twenty-three rabbits were imaged approximately 72 hours after infusion of i.v. norepinephrine. Diffuse cardiac uptake was found in 13 of 15 rabbits scanned with 67Ga. Tissue distribution studies documented significant myocardial uptake of 67Ga in those with pos...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2006
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2006.08.017